null
SMILES: Clc1ccc(cc1)-c1ccc(o1)C(=O)N1CCCc2ccccc12
InChI Key: InChIKey=LBAPJZXPMNVOTD-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human)) | BDBM50466957 (CHEMBL4172687) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.13E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
South China Agricultural University Curated by ChEMBL | Assay Description Inhibition of human U937 cells-derived PDE4D using [3H]-cAMP as substrate after 30 mins | Bioorg Med Chem Lett 28: 3271-3275 (2018) Article DOI: 10.1016/j.bmcl.2018.04.068 BindingDB Entry DOI: 10.7270/Q2057JMP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM50466957 (CHEMBL4172687) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
South China Agricultural University Curated by ChEMBL | Assay Description Inhibition of human U937 cells-derived PDE4B using [3H]-cAMP as substrate after 30 mins | Bioorg Med Chem Lett 28: 3271-3275 (2018) Article DOI: 10.1016/j.bmcl.2018.04.068 BindingDB Entry DOI: 10.7270/Q2057JMP | |||||||||||
More data for this Ligand-Target Pair |