null

SMILES: COc1ccc(Nc2cc(NC(=O)c3ccccc3)ncn2)cc1

InChI Key: InChIKey=GPHGJEXSAYLLDB-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50467152   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50467152 (CHEMBL4283823) Show SMILES COc1ccc(Nc2cc(NC(=O)c3ccccc3)ncn2)cc1 Show InChI InChI=1S/C18H16N4O2/c1-24-15-9-7-14(8-10-15)21-16-11-17(20-12-19-16)22-18(23)13-5-3-2-4-6-13/h2-12H,1H3,(H2,19,20,21,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	81	n/a	n/a	n/a	n/a	n/a	n/a
Wenzhou Medical University Curated by ChEMBL					Assay Description Inhibition of N-terminal GST-tagged wild type human EGFR cytoplasmic domain (669 to 1210 residues) expressed in baculovirus expression system using F...				Eur J Med Chem 157: 1300-1325 (2018) Article DOI: 10.1016/j.ejmech.2018.08.031 BindingDB Entry DOI: 10.7270/Q2SF2ZVS
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50467152 (CHEMBL4283823) Show SMILES COc1ccc(Nc2cc(NC(=O)c3ccccc3)ncn2)cc1 Show InChI InChI=1S/C18H16N4O2/c1-24-15-9-7-14(8-10-15)21-16-11-17(20-12-19-16)22-18(23)13-5-3-2-4-6-13/h2-12H,1H3,(H2,19,20,21,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
Wenzhou Medical University Curated by ChEMBL					Assay Description Inhibition of N-terminal GST-tagged human EGFR del 747-750 mutant cytoplasmic domain expressed in baculovirus expression system using FAM-labeled pep...				Eur J Med Chem 157: 1300-1325 (2018) Article DOI: 10.1016/j.ejmech.2018.08.031 BindingDB Entry DOI: 10.7270/Q2SF2ZVS
					More data for this Ligand-Target Pair
Receptor tyrosine-protein kinase erbB-3 (Homo sapiens (Human))	BDBM50467152 (CHEMBL4283823) Show SMILES COc1ccc(Nc2cc(NC(=O)c3ccccc3)ncn2)cc1 Show InChI InChI=1S/C18H16N4O2/c1-24-15-9-7-14(8-10-15)21-16-11-17(20-12-19-16)22-18(23)13-5-3-2-4-6-13/h2-12H,1H3,(H2,19,20,21,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Wenzhou Medical University Curated by ChEMBL					Assay Description Inhibition of recombinant human GST-tagged EGFR L858R mutant cytoplasmic domain expressed in baculovirus expression system using FAM-labeled peptide ...				Eur J Med Chem 157: 1300-1325 (2018) Article DOI: 10.1016/j.ejmech.2018.08.031 BindingDB Entry DOI: 10.7270/Q2SF2ZVS
					More data for this Ligand-Target Pair