null

SMILES: CCOC(=O)c1ccc(Nc2cc(Nc3cccc(OC)c3)ncn2)cc1

InChI Key: InChIKey=XCGNJKSVDJJZLW-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50467157   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50467157 (CHEMBL4292110) Show SMILES CCOC(=O)c1ccc(Nc2cc(Nc3cccc(OC)c3)ncn2)cc1 Show InChI InChI=1S/C20H20N4O3/c1-3-27-20(25)14-7-9-15(10-8-14)23-18-12-19(22-13-21-18)24-16-5-4-6-17(11-16)26-2/h4-13H,3H2,1-2H3,(H2,21,22,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wenzhou Medical University Curated by ChEMBL					Assay Description Inhibition of N-terminal GST-tagged wild type human EGFR cytoplasmic domain (669 to 1210 residues) expressed in baculovirus expression system using F...				Eur J Med Chem 157: 1300-1325 (2018) Article DOI: 10.1016/j.ejmech.2018.08.031 BindingDB Entry DOI: 10.7270/Q2SF2ZVS
					More data for this Ligand-Target Pair
Receptor tyrosine-protein kinase erbB-3 (Homo sapiens (Human))	BDBM50467157 (CHEMBL4292110) Show SMILES CCOC(=O)c1ccc(Nc2cc(Nc3cccc(OC)c3)ncn2)cc1 Show InChI InChI=1S/C20H20N4O3/c1-3-27-20(25)14-7-9-15(10-8-14)23-18-12-19(22-13-21-18)24-16-5-4-6-17(11-16)26-2/h4-13H,3H2,1-2H3,(H2,21,22,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.75E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wenzhou Medical University Curated by ChEMBL					Assay Description Inhibition of recombinant human GST-tagged EGFR L858R mutant cytoplasmic domain expressed in baculovirus expression system using FAM-labeled peptide ...				Eur J Med Chem 157: 1300-1325 (2018) Article DOI: 10.1016/j.ejmech.2018.08.031 BindingDB Entry DOI: 10.7270/Q2SF2ZVS
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50467157 (CHEMBL4292110) Show SMILES CCOC(=O)c1ccc(Nc2cc(Nc3cccc(OC)c3)ncn2)cc1 Show InChI InChI=1S/C20H20N4O3/c1-3-27-20(25)14-7-9-15(10-8-14)23-18-12-19(22-13-21-18)24-16-5-4-6-17(11-16)26-2/h4-13H,3H2,1-2H3,(H2,21,22,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.19E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wenzhou Medical University Curated by ChEMBL					Assay Description Inhibition of N-terminal GST-tagged human EGFR del 747-750 mutant cytoplasmic domain expressed in baculovirus expression system using FAM-labeled pep...				Eur J Med Chem 157: 1300-1325 (2018) Article DOI: 10.1016/j.ejmech.2018.08.031 BindingDB Entry DOI: 10.7270/Q2SF2ZVS
					More data for this Ligand-Target Pair