null

SMILES: OC(=O)CCCC(=O)Nc1cc(Nc2ccccc2)ncn1

InChI Key: InChIKey=ACTXRPZBCPTJSQ-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50467161   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50467161 (CHEMBL4278997) Show SMILES OC(=O)CCCC(=O)Nc1cc(Nc2ccccc2)ncn1 Show InChI InChI=1S/C15H16N4O3/c20-14(7-4-8-15(21)22)19-13-9-12(16-10-17-13)18-11-5-2-1-3-6-11/h1-3,5-6,9-10H,4,7-8H2,(H,21,22)(H2,16,17,18,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wenzhou Medical University Curated by ChEMBL					Assay Description Inhibition of N-terminal GST-tagged wild type human EGFR cytoplasmic domain (669 to 1210 residues) expressed in baculovirus expression system using F...				Eur J Med Chem 157: 1300-1325 (2018) Article DOI: 10.1016/j.ejmech.2018.08.031 BindingDB Entry DOI: 10.7270/Q2SF2ZVS
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50467161 (CHEMBL4278997) Show SMILES OC(=O)CCCC(=O)Nc1cc(Nc2ccccc2)ncn1 Show InChI InChI=1S/C15H16N4O3/c20-14(7-4-8-15(21)22)19-13-9-12(16-10-17-13)18-11-5-2-1-3-6-11/h1-3,5-6,9-10H,4,7-8H2,(H,21,22)(H2,16,17,18,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	105	n/a	n/a	n/a	n/a	n/a	n/a
Wenzhou Medical University Curated by ChEMBL					Assay Description Inhibition of N-terminal GST-tagged human EGFR del 747-750 mutant cytoplasmic domain expressed in baculovirus expression system using FAM-labeled pep...				Eur J Med Chem 157: 1300-1325 (2018) Article DOI: 10.1016/j.ejmech.2018.08.031 BindingDB Entry DOI: 10.7270/Q2SF2ZVS
					More data for this Ligand-Target Pair
Receptor tyrosine-protein kinase erbB-3 (Homo sapiens (Human))	BDBM50467161 (CHEMBL4278997) Show SMILES OC(=O)CCCC(=O)Nc1cc(Nc2ccccc2)ncn1 Show InChI InChI=1S/C15H16N4O3/c20-14(7-4-8-15(21)22)19-13-9-12(16-10-17-13)18-11-5-2-1-3-6-11/h1-3,5-6,9-10H,4,7-8H2,(H,21,22)(H2,16,17,18,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	183	n/a	n/a	n/a	n/a	n/a	n/a
Wenzhou Medical University Curated by ChEMBL					Assay Description Inhibition of recombinant human GST-tagged EGFR L858R mutant cytoplasmic domain expressed in baculovirus expression system using FAM-labeled peptide ...				Eur J Med Chem 157: 1300-1325 (2018) Article DOI: 10.1016/j.ejmech.2018.08.031 BindingDB Entry DOI: 10.7270/Q2SF2ZVS
					More data for this Ligand-Target Pair