BDBM50467593 CHEMBL4284259
SMILES: Cc1csc(NC(=O)c2ccc(CNc3ccccc3C)cc2)n1
InChI Key: InChIKey=DHPPBCAZAYICNH-UHFFFAOYSA-N
Data: 3 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Stearoyl-CoA desaturase 1 (Homo sapiens (Human)) | BDBM50467593 (CHEMBL4284259) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 6.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Japan Tobacco Inc. Curated by ChEMBL | Assay Description Inhibition of recombinant human SCD1 expressed in baculovirus expression system assessed as reduction in [3H]H2O production using stearoyl [9,10-3H]C... | Eur J Med Chem 158: 832-852 (2018) Article DOI: 10.1016/j.ejmech.2018.09.003 BindingDB Entry DOI: 10.7270/Q21V5HN5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acyl-CoA desaturase 1 (Mus musculus) | BDBM50467593 (CHEMBL4284259) | PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Japan Tobacco Inc. Curated by ChEMBL | Assay Description Inhibition of mouse liver microsome SCD assessed as reduction in [3H]H2O production using stearoyl [9,10-3H]CoA as substrate in presence of NADH incu... | Eur J Med Chem 158: 832-852 (2018) Article DOI: 10.1016/j.ejmech.2018.09.003 BindingDB Entry DOI: 10.7270/Q21V5HN5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fatty acid desaturase 1 (Homo sapiens (Human)) | BDBM50467593 (CHEMBL4284259) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Japan Tobacco Inc. Curated by ChEMBL | Assay Description Inhibition of delta-5 fatty acid desaturase (unknown origin) | Eur J Med Chem 158: 832-852 (2018) Article DOI: 10.1016/j.ejmech.2018.09.003 BindingDB Entry DOI: 10.7270/Q21V5HN5 | |||||||||||
More data for this Ligand-Target Pair |