BDBM50467683 CHEMBL4286253

SMILES: Cc1ccc(NC(=O)c2ccc(c(OCCCCn3ccnc3)c2)[N+]([O-])=O)cc1Nc1nccc(n1)-c1cccnc1

InChI Key: InChIKey=SMUIUUIKJMXBAL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50467683   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Heme oxygenase 1 (Rattus norvegicus (rat))	BDBM50467683 (CHEMBL4286253) Show SMILES Cc1ccc(NC(=O)c2ccc(c(OCCCCn3ccnc3)c2)[N+]([O-])=O)cc1Nc1nccc(n1)-c1cccnc1 Show InChI InChI=1S/C30H28N8O4/c1-21-6-8-24(18-26(21)36-30-33-12-10-25(35-30)23-5-4-11-31-19-23)34-29(39)22-7-9-27(38(40)41)28(17-22)42-16-3-2-14-37-15-13-32-20-37/h4-13,15,17-20H,2-3,14,16H2,1H3,(H,34,39)(H,33,35,36)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.03E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Catania Curated by ChEMBL					Assay Description Inhibition of heme oxygenase 1 in Sprague-Dawley rat spleen microsomal fraction assessed as decrease in bilirubin formation using biliverdin reductas...				Eur J Med Chem 158: 937-950 (2018) Article DOI: 10.1016/j.ejmech.2018.09.048 BindingDB Entry DOI: 10.7270/Q2NK3HQ4
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