BDBM50467694 CHEMBL4294817

SMILES: CC(Cn1ncc2c(Nc3cc(O)ccc3Cl)nc(NCCO)nc12)c1ccccc1

InChI Key: InChIKey=ZAZXISVLNYMWGS-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50467694   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50467694 (CHEMBL4294817) Show SMILES CC(Cn1ncc2c(Nc3cc(O)ccc3Cl)nc(NCCO)nc12)c1ccccc1 Show InChI InChI=1S/C22H23ClN6O2/c1-14(15-5-3-2-4-6-15)13-29-21-17(12-25-29)20(27-22(28-21)24-9-10-30)26-19-11-16(31)7-8-18(19)23/h2-8,11-12,14,30-31H,9-10,13H2,1H3,(H2,24,26,27,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	23	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Inhibition of human c-Src using KVEKIGEGTYGVVYK as substrate in presence of [gamma32P]ATP by scintillation counting method				Bioorg Med Chem Lett 28: 3454-3457 (2018) Article DOI: 10.1016/j.bmcl.2018.09.024 BindingDB Entry DOI: 10.7270/Q2HT2S18
					More data for this Ligand-Target Pair