BindingDB logo
myBDB logout

null

SMILES: Oc1cccc(Nc2nc(SCCN3CCOCC3)nc3n(CC(Cl)c4ccccc4)ncc23)c1

InChI Key: InChIKey=IEYDYHPFPKSECG-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50467702   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))		BDBM50467702
PNG
(CHEMBL4283149)
Show SMILES Oc1cccc(Nc2nc(SCCN3CCOCC3)nc3n(CC(Cl)c4ccccc4)ncc23)c1
Show InChI InChI=1S/C25H27ClN6O2S/c26-22(18-5-2-1-3-6-18)17-32-24-21(16-27-32)23(28-19-7-4-8-20(33)15-19)29-25(30-24)35-14-11-31-9-12-34-13-10-31/h1-8,15-16,22,33H,9-14,17H2,(H,28,29,30)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
 190n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Siena

Curated by ChEMBL


Assay Description
Inhibition of human c-Src using KVEKIGEGTYGVVYK as substrate in presence of [gamma32P]ATP by scintillation counting method

Bioorg Med Chem Lett 28: 3454-3457 (2018)


Article DOI: 10.1016/j.bmcl.2018.09.024
BindingDB Entry DOI: 10.7270/Q2HT2S18
More data for this
Ligand-Target Pair