BDBM50468142 CHEMBL4280432

SMILES: Cc1cc(c(CN2CCC3(CN(C(=O)C3)c3ccc(cc3)C(O)=O)CC2)cc1C(F)(F)F)-c1ccc(F)c(F)c1F

InChI Key: InChIKey=HSXIPZDTFGIFKD-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50468142   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Somatostatin receptor type 5 (Homo sapiens (Human))	BDBM50468142 (CHEMBL4280432) Show SMILES Cc1cc(c(CN2CCC3(CN(C(=O)C3)c3ccc(cc3)C(O)=O)CC2)cc1C(F)(F)F)-c1ccc(F)c(F)c1F Show InChI InChI=1S/C30H26F6N2O3/c1-17-12-22(21-6-7-24(31)27(33)26(21)32)19(13-23(17)30(34,35)36)15-37-10-8-29(9-11-37)14-25(39)38(16-29)20-4-2-18(3-5-20)28(40)41/h2-7,12-13H,8-11,14-16H2,1H3,(H,40,41)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.90	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co. Curated by ChEMBL					Assay Description Displacement of [3-125I-Tyr11]-SRIF-14 or [3-125I-Tyr11]-SRIF-28 from human SSR5 expressed in CHOK1 cell membranes				ACS Med Chem Lett 9: 1088-1093 (2018) Article DOI: 10.1021/acsmedchemlett.8b00306 BindingDB Entry DOI: 10.7270/Q2V127H3
					More data for this Ligand-Target Pair
Somatostatin receptor (Mus musculus)	BDBM50468142 (CHEMBL4280432) Show SMILES Cc1cc(c(CN2CCC3(CN(C(=O)C3)c3ccc(cc3)C(O)=O)CC2)cc1C(F)(F)F)-c1ccc(F)c(F)c1F Show InChI InChI=1S/C30H26F6N2O3/c1-17-12-22(21-6-7-24(31)27(33)26(21)32)19(13-23(17)30(34,35)36)15-37-10-8-29(9-11-37)14-25(39)38(16-29)20-4-2-18(3-5-20)28(40)41/h2-7,12-13H,8-11,14-16H2,1H3,(H,40,41)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co. Curated by ChEMBL					Assay Description Antagonist activity at mouse SSR5 expressed in CHOK1 cells assessed as inhibition of forskolin-induced cAMP accumulation preincubated for 15 mins fol...				ACS Med Chem Lett 9: 1088-1093 (2018) Article DOI: 10.1021/acsmedchemlett.8b00306 BindingDB Entry DOI: 10.7270/Q2V127H3
					More data for this Ligand-Target Pair
Somatostatin receptor type 5 (Homo sapiens (Human))	BDBM50468142 (CHEMBL4280432) Show SMILES Cc1cc(c(CN2CCC3(CN(C(=O)C3)c3ccc(cc3)C(O)=O)CC2)cc1C(F)(F)F)-c1ccc(F)c(F)c1F Show InChI InChI=1S/C30H26F6N2O3/c1-17-12-22(21-6-7-24(31)27(33)26(21)32)19(13-23(17)30(34,35)36)15-37-10-8-29(9-11-37)14-25(39)38(16-29)20-4-2-18(3-5-20)28(40)41/h2-7,12-13H,8-11,14-16H2,1H3,(H,40,41)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co. Curated by ChEMBL					Assay Description Antagonist activity at human SSR5 expressed in CHOK1 cells assessed as inhibition of forskolin-induced cAMP accumulation preincubated for 15 mins fol...				ACS Med Chem Lett 9: 1088-1093 (2018) Article DOI: 10.1021/acsmedchemlett.8b00306 BindingDB Entry DOI: 10.7270/Q2V127H3
					More data for this Ligand-Target Pair