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SMILES: OC(=O)CC[C@H](NC(=O)N[C@@H](CCCC(=O)Nc1cccc(F)c1)C(O)=O)C(O)=O

InChI Key: InChIKey=XXSKDWRQIMQLKQ-STQMWFEESA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50468174   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glutamate carboxypeptidase 2


(Homo sapiens (Human))		BDBM50468174
PNG
(CHEMBL4277729)
Show SMILES OC(=O)CC[C@H](NC(=O)N[C@@H](CCCC(=O)Nc1cccc(F)c1)C(O)=O)C(O)=O |r|
Show InChI InChI=1S/C18H22FN3O8/c19-10-3-1-4-11(9-10)20-14(23)6-2-5-12(16(26)27)21-18(30)22-13(17(28)29)7-8-15(24)25/h1,3-4,9,12-13H,2,5-8H2,(H,20,23)(H,24,25)(H,26,27)(H,28,29)(H2,21,22,30)/t12-,13-/m0/s1
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MMDB

KEGG

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 0.280n/an/an/an/an/an/a



University of Illinois at Chicago

Curated by ChEMBL


Assay Description
Inhibition of recombinant human PSMA using [3H]NAAG as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins by li...

ACS Med Chem Lett 9: 1099-1104 (2018)


Article DOI: 10.1021/acsmedchemlett.8b00318
BindingDB Entry DOI: 10.7270/Q2Q81GSC
More data for this
Ligand-Target Pair