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SMILES: CN(Cc1ccc(F)cc1)C(=O)CCC[C@H](NC(=O)N[C@@H](CCC(O)=O)C(O)=O)C(O)=O

InChI Key: InChIKey=GGVPFHXSAFBMAX-GJZGRUSLSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50468178   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glutamate carboxypeptidase 2


(Homo sapiens (Human))		BDBM50468178
PNG
(CHEMBL4283406)
Show SMILES CN(Cc1ccc(F)cc1)C(=O)CCC[C@H](NC(=O)N[C@@H](CCC(O)=O)C(O)=O)C(O)=O |r|
Show InChI InChI=1S/C20H26FN3O8/c1-24(11-12-5-7-13(21)8-6-12)16(25)4-2-3-14(18(28)29)22-20(32)23-15(19(30)31)9-10-17(26)27/h5-8,14-15H,2-4,9-11H2,1H3,(H,26,27)(H,28,29)(H,30,31)(H2,22,23,32)/t14-,15-/m0/s1
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MMDB

KEGG

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 0.640n/an/an/an/an/an/a



University of Illinois at Chicago

Curated by ChEMBL


Assay Description
Inhibition of recombinant human PSMA using [3H]NAAG as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins by li...

ACS Med Chem Lett 9: 1099-1104 (2018)


Article DOI: 10.1021/acsmedchemlett.8b00318
BindingDB Entry DOI: 10.7270/Q2Q81GSC
More data for this
Ligand-Target Pair