null

SMILES: O=C(Nc1nccs1)C(N1Cc2ccccc2C1=O)c1ccccc1

InChI Key: InChIKey=PWRVRDCBFYLYFU-UHFFFAOYSA-N

PDB links: 3 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50468244   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50468244 (CHEMBL4284413) Show SMILES O=C(Nc1nccs1)C(N1Cc2ccccc2C1=O)c1ccccc1 Show InChI InChI=1S/C19H15N3O2S/c23-17(21-19-20-10-11-25-19)16(13-6-2-1-3-7-13)22-12-14-8-4-5-9-15(14)18(22)24/h1-11,16H,12H2,(H,20,21,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
R. C. Patel Institute of Pharmaceutical Education and Research Curated by ChEMBL					Assay Description Inhibition of human wild type EGFR expressed in Sf9 cells in presence of 1 mM ATP by HTRF assay				Eur J Med Chem 142: 32-47 (2017) Article DOI: 10.1016/j.ejmech.2017.05.027 BindingDB Entry DOI: 10.7270/Q2T156B8
					More data for this Ligand-Target Pair				3D Structure (crystal)
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50468244 (CHEMBL4284413) Show SMILES O=C(Nc1nccs1)C(N1Cc2ccccc2C1=O)c1ccccc1 Show InChI InChI=1S/C19H15N3O2S/c23-17(21-19-20-10-11-25-19)16(13-6-2-1-3-7-13)22-12-14-8-4-5-9-15(14)18(22)24/h1-11,16H,12H2,(H,20,21,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
R. C. Patel Institute of Pharmaceutical Education and Research Curated by ChEMBL					Assay Description Inhibition of human EGFR L858R mutant expressed in Sf9 cells in presence of 1 mM ATP by HTRF assay				Eur J Med Chem 142: 32-47 (2017) Article DOI: 10.1016/j.ejmech.2017.05.027 BindingDB Entry DOI: 10.7270/Q2T156B8
					More data for this Ligand-Target Pair				3D Structure (crystal)