BDBM50468486 CHEMBL4281274

SMILES: O=C(NNc1nc2ccccc2n2cnnc12)Nc1ccccc1

InChI Key: InChIKey=CVQYVOQNUKBPDU-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50468486   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Topoisomerase I/II (Homo sapiens (Human))	BDBM50468486 (CHEMBL4281274) Show SMILES O=C(NNc1nc2ccccc2n2cnnc12)Nc1ccccc1 Show InChI InChI=1S/C16H13N7O/c24-16(18-11-6-2-1-3-7-11)22-20-14-15-21-17-10-23(15)13-9-5-4-8-12(13)19-14/h1-10H,(H,19,20)(H2,18,22,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.19E+3	n/a	n/a	n/a	n/a	n/a	n/a
Al-Azhar University Curated by ChEMBL					Assay Description Inhibition of human topoisomerase 2 using supercoiled pHOT1 DNA as substrate after 30 mins by agarose gel electrophoresis				Eur J Med Chem 155: 117-134 (2018) Article DOI: 10.1016/j.ejmech.2018.06.004 BindingDB Entry DOI: 10.7270/Q2TT4TN9
					More data for this Ligand-Target Pair