BDBM50468487 CHEMBL4284675

SMILES: CCNC(=S)NNc1nc2ccccc2n2cnnc12

InChI Key: InChIKey=SZLLOCDHVKXZGF-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50468487   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Topoisomerase I/II (Homo sapiens (Human))	BDBM50468487 (CHEMBL4284675) Show SMILES CCNC(=S)NNc1nc2ccccc2n2cnnc12 Show InChI InChI=1S/C12H13N7S/c1-2-13-12(20)18-16-10-11-17-14-7-19(11)9-6-4-3-5-8(9)15-10/h3-7H,2H2,1H3,(H,15,16)(H2,13,18,20)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.38E+3	n/a	n/a	n/a	n/a	n/a	n/a
Al-Azhar University Curated by ChEMBL					Assay Description Inhibition of human topoisomerase 2 using supercoiled pHOT1 DNA as substrate after 30 mins by agarose gel electrophoresis				Eur J Med Chem 155: 117-134 (2018) Article DOI: 10.1016/j.ejmech.2018.06.004 BindingDB Entry DOI: 10.7270/Q2TT4TN9
					More data for this Ligand-Target Pair