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BDBM50468513 CHEMBL4280367

SMILES: COc1ccc(Oc2cc3n(C)c(=O)c(=O)n(C)c3cc2NC(=O)c2ccccc2F)cc1

InChI Key: InChIKey=HVIOREYDAKXEQU-UHFFFAOYSA-N

Data: 1 Kd

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50468513   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Peregrin


(Homo sapiens (Human))		BDBM50468513
PNG
(CHEMBL4280367)
Show SMILES COc1ccc(Oc2cc3n(C)c(=O)c(=O)n(C)c3cc2NC(=O)c2ccccc2F)cc1
Show InChI InChI=1S/C24H20FN3O5/c1-27-19-12-18(26-22(29)16-6-4-5-7-17(16)25)21(13-20(19)28(2)24(31)23(27)30)33-15-10-8-14(32-3)9-11-15/h4-13H,1-3H3,(H,26,29)
PDB

KEGG

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
Article
PubMed
n/an/an/a>2.50E+4n/an/an/an/an/a



University of Zurich

Curated by ChEMBL


Assay Description
Binding affinity to human partial length BRPF1 (E627 to G740 residues) expressed in Escherichia coli BL21 after 1 hr by BROMOscan assay

Eur J Med Chem 155: 337-352 (2018)


Article DOI: 10.1016/j.ejmech.2018.05.037
BindingDB Entry DOI: 10.7270/Q2FJ2KG7
More data for this
Ligand-Target Pair