BDBM50468955 CHEMBL4286987

SMILES: Fc1ccccc1-c1ccc2nc(-c3ccco3)c(nc2c1)-c1ccco1

InChI Key: InChIKey=LVFBZKVCTOEJHZ-UHFFFAOYSA-N

Data: 1 EC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50468955   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50468955 (CHEMBL4286987) Show SMILES Fc1ccccc1-c1ccc2nc(-c3ccco3)c(nc2c1)-c1ccco1 Show InChI InChI=1S/C22H13FN2O2/c23-16-6-2-1-5-15(16)14-9-10-17-18(13-14)25-22(20-8-4-12-27-20)21(24-17)19-7-3-11-26-19/h1-13H	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	1.27E+4	n/a	n/a	n/a	n/a
Chongqing University Curated by ChEMBL					Assay Description Inhibition of recombinant full length PI3K p85alpha/p110alpha H1047R mutant (unknown origin) expressed in baculovirus infected sf9 cells using PIP2 a...				Eur J Med Chem 157: 37-49 (2018) Article DOI: 10.1016/j.ejmech.2018.07.061 BindingDB Entry DOI: 10.7270/Q2ZC85KT
					More data for this Ligand-Target Pair