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BDBM50469025 CHEMBL4293473

SMILES: Clc1ccc(NC(=O)Nc2nccnc2OCc2ccccc2)cc1Cl

InChI Key: InChIKey=NKLIKNZUXBGVIF-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50469025   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
1,3-beta-glucan synthase component GLS2


(Saccharomyces cerevisiae)		BDBM50469025
PNG
(CHEMBL4293473)
Show SMILES Clc1ccc(NC(=O)Nc2nccnc2OCc2ccccc2)cc1Cl
Show InChI InChI=1S/C18H14Cl2N4O2/c19-14-7-6-13(10-15(14)20)23-18(25)24-16-17(22-9-8-21-16)26-11-12-4-2-1-3-5-12/h1-10H,11H2,(H2,21,23,24,25)
KEGG

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.13E+4n/an/an/an/an/an/a



Korea Institute of Science and Technology (KIST)

Curated by ChEMBL


Assay Description
Displacement of [3H]-astemizole from human ERG expressed in HEK293 cell membranes after 1 hr by microbeta counting method

Eur J Med Chem 157: 268-278 (2018)


Article DOI: 10.1016/j.ejmech.2018.07.068
BindingDB Entry DOI: 10.7270/Q25X2CN9
More data for this
Ligand-Target Pair