BDBM50469122 CHEMBL4278637

SMILES: [#8]-c1cccc(\[#6]=[#6]-2\c3ccccc3-[#6](=O)-c3ccccc-23)c1

InChI Key: InChIKey=KGQNBZACENOOOR-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50469122   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Androgen Receptor (Homo sapiens (Human))	BDBM50469122 (CHEMBL4278637) Show SMILES [#8]-c1cccc(\[#6]=[#6]-2\c3ccccc3-[#6](=O)-c3ccccc-23)c1 Show InChI InChI=1S/C21H14O2/c22-15-7-5-6-14(12-15)13-20-16-8-1-3-10-18(16)21(23)19-11-4-2-9-17(19)20/h1-13,22H	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	316	n/a	n/a	n/a	n/a	n/a	n/a
Vancouver Prostate Centre (VPC) Curated by ChEMBL					Assay Description Inhibition of R1881-induced full length AR transcriptional activity in human LNCAP cells harboring AR2PB-eGFP construct after 72 hrs by fluorescence ...				Eur J Med Chem 157: 1164-1173 (2018) Article DOI: 10.1016/j.ejmech.2018.08.059 BindingDB Entry DOI: 10.7270/Q2183967
					More data for this Ligand-Target Pair
Androgen Receptor (Homo sapiens (Human))	BDBM50469122 (CHEMBL4278637) Show SMILES [#8]-c1cccc(\[#6]=[#6]-2\c3ccccc3-[#6](=O)-c3ccccc-23)c1 Show InChI InChI=1S/C21H14O2/c22-15-7-5-6-14(12-15)13-20-16-8-1-3-10-18(16)21(23)19-11-4-2-9-17(19)20/h1-13,22H	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	<1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vancouver Prostate Centre (VPC) Curated by ChEMBL					Assay Description Inhibition of R1881-induced transcriptional activity of human AR V7 truncated mutant expressed in human PC3 cells harboring pGL3-ARR3tk-NLuc after 24...				Eur J Med Chem 157: 1164-1173 (2018) Article DOI: 10.1016/j.ejmech.2018.08.059 BindingDB Entry DOI: 10.7270/Q2183967
					More data for this Ligand-Target Pair
Androgen Receptor (Homo sapiens (Human))	BDBM50469122 (CHEMBL4278637) Show SMILES [#8]-c1cccc(\[#6]=[#6]-2\c3ccccc3-[#6](=O)-c3ccccc-23)c1 Show InChI InChI=1S/C21H14O2/c22-15-7-5-6-14(12-15)13-20-16-8-1-3-10-18(16)21(23)19-11-4-2-9-17(19)20/h1-13,22H	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	350	n/a	n/a	n/a	n/a	n/a	n/a
Vancouver Prostate Centre (VPC) Curated by ChEMBL					Assay Description Inhibition of full length AR transcriptional activity in human LNCAP cells harboring AR2PB-eGFP construct assessed as reduction in R1881-induced secr...				Eur J Med Chem 157: 1164-1173 (2018) Article DOI: 10.1016/j.ejmech.2018.08.059 BindingDB Entry DOI: 10.7270/Q2183967
					More data for this Ligand-Target Pair
Androgen Receptor (Rattus norvegicus (Rat))	BDBM50469122 (CHEMBL4278637) Show SMILES [#8]-c1cccc(\[#6]=[#6]-2\c3ccccc3-[#6](=O)-c3ccccc-23)c1 Show InChI InChI=1S/C21H14O2/c22-15-7-5-6-14(12-15)13-20-16-8-1-3-10-18(16)21(23)19-11-4-2-9-17(19)20/h1-13,22H	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	625	n/a	n/a	n/a	n/a	n/a	n/a
Vancouver Prostate Centre (VPC) Curated by ChEMBL					Assay Description Displacement of Fluormone-DHT from rat GST-tagged rat AR LBD expressed in insect cells after 4 hrs by fluorescence polarization assay				Eur J Med Chem 157: 1164-1173 (2018) Article DOI: 10.1016/j.ejmech.2018.08.059 BindingDB Entry DOI: 10.7270/Q2183967
					More data for this Ligand-Target Pair