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SMILES: [O-][N+](=O)c1ccccc1CN1c2ccccc2SC(CC1=O)c1ccc(cc1)C(=O)NCc1cccc(Cl)c1

InChI Key: InChIKey=CWXKEXZGEDXZRU-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50469302   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Glycogen synthase kinase-3 beta


(Homo sapiens (Human))		BDBM50469302
PNG
(CHEMBL4279766)
Show SMILES [O-][N+](=O)c1ccccc1CN1c2ccccc2SC(CC1=O)c1ccc(cc1)C(=O)NCc1cccc(Cl)c1
Show InChI InChI=1S/C30H24ClN3O4S/c31-24-8-5-6-20(16-24)18-32-30(36)22-14-12-21(13-15-22)28-17-29(35)33(26-10-3-4-11-27(26)39-28)19-23-7-1-2-9-25(23)34(37)38/h1-16,28H,17-19H2,(H,32,36)
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PC cid
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Article
PubMed
n/an/a 3.50E+4n/an/an/an/an/an/a



Fudan University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant N-terminal His6-tagged human GSK-3beta expressed in Baculovirus infected SF9 cells using prephosphorylated-GS2 polype...

Bioorg Med Chem 26: 5479-5493 (2018)


Article DOI: 10.1016/j.bmc.2018.09.027
BindingDB Entry DOI: 10.7270/Q2319ZMZ
More data for this
Ligand-Target Pair