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SMILES: CC(C)C[C@H](NC(=O)[C@@H](CCCCNC(=O)c1cccnc1)NC(=O)[C@H](Cc1ccc(O)cc1)N(C)C(=O)[C@H](CO)NC(=O)[C@H](Cc1cccc2ccccc12)NC(=O)CCc1ccc(F)cc1)C(=O)N[C@@H](CCCCNC(C)C)C(=O)N1CCC[C@@H]1C(N)=O

InChI Key: InChIKey=SENLFDBSRSOZPP-NDDGHMPHSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50470118   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Gonadotropin-releasing hormone receptor


(Rattus norvegicus)		BDBM50470118
PNG
(CHEMBL412751)
Show SMILES CC(C)C[C@H](NC(=O)[C@@H](CCCCNC(=O)c1cccnc1)NC(=O)[C@H](Cc1ccc(O)cc1)N(C)C(=O)[C@H](CO)NC(=O)[C@H](Cc1cccc2ccccc12)NC(=O)CCc1ccc(F)cc1)C(=O)N[C@@H](CCCCNC(C)C)C(=O)N1CCC[C@@H]1C(N)=O
Show InChI InChI=1S/C67H88FN11O11/c1-42(2)37-54(63(86)75-53(21-9-10-34-71-43(3)4)67(90)79-36-14-22-57(79)60(69)83)76-62(85)52(20-8-11-35-72-61(84)48-18-13-33-70-40-48)74-65(88)58(38-45-25-30-50(81)31-26-45)78(5)66(89)56(41-80)77-64(87)55(39-47-17-12-16-46-15-6-7-19-51(46)47)73-59(82)32-27-44-23-28-49(68)29-24-44/h6-7,12-13,15-19,23-26,28-31,33,40,42-43,52-58,71,80-81H,8-11,14,20-22,27,32,34-39,41H2,1-5H3,(H2,69,83)(H,72,84)(H,73,82)(H,74,88)(H,75,86)(H,76,85)(H,77,87)/t52-,53+,54+,55+,56+,57-,58+/m1/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
 0.0160n/an/an/an/an/an/an/an/a



TAP Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Inhibition of the in vitro binding of [125I]-labeled leuprolide to the rat pituitary luteinizing hormone releasing hormone (LHRH) receptor.

J Med Chem 37: 701-5 (1994)


Article DOI: 10.1021/jm00031a021
BindingDB Entry DOI: 10.7270/Q2MG7S7B
More data for this
Ligand-Target Pair