BindingDB logo
myBDB logout

null

SMILES: CN(C)CCCOc1ccc(NC(=O)COc2ccc(Cl)cc2C(=O)c2ccccc2)cc1

InChI Key: InChIKey=WWJUGOBLSKHMSA-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50470138   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Reverse transcriptase/RNaseH


(Human immunodeficiency virus 1)		BDBM50470138
PNG
(CHEMBL46650)
Show SMILES CN(C)CCCOc1ccc(NC(=O)COc2ccc(Cl)cc2C(=O)c2ccccc2)cc1
Show InChI InChI=1S/C26H27ClN2O4/c1-29(2)15-6-16-32-22-12-10-21(11-13-22)28-25(30)18-33-24-14-9-20(27)17-23(24)26(31)19-7-4-3-5-8-19/h3-5,7-14,17H,6,15-16,18H2,1-2H3,(H,28,30)
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 207n/an/an/an/an/an/a



Glaxo Research and Development Limited

Curated by ChEMBL


Assay Description
Inhibitory activity against HIV-1 reverse transcriptase

J Med Chem 38: 1657-65 (1995)


Article DOI: 10.1021/jm00010a010
BindingDB Entry DOI: 10.7270/Q27947DP
More data for this
Ligand-Target Pair