BDBM50470158 CHEMBL4103716

SMILES: Cc1nnc(o1)-c1cc(cnc1N)-c1ccc2[nH]ccc2c1

InChI Key: InChIKey=NYHUATBNBRNLQG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50470158   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human))	BDBM50470158 (CHEMBL4103716) Show SMILES Cc1nnc(o1)-c1cc(cnc1N)-c1ccc2[nH]ccc2c1 Show InChI InChI=1S/C16H13N5O/c1-9-20-21-16(22-9)13-7-12(8-19-15(13)17)10-2-3-14-11(6-10)4-5-18-14/h2-8,18H,1H3,(H2,17,19)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S, Ottiliavej 9, 2500 Valby, Denmark. Electronic address: gsm@lundbeck.com. Curated by ChEMBL					Assay Description Inhibition of recombinant human LRRK2 (970 to 2527 residues) G2019S mutant expressed in baculovirus preincubated for 30 mins followed by fluorescein-...				Bioorg Med Chem Lett 27: 4500-4505 (2017) Article DOI: 10.1016/j.bmcl.2017.07.072 BindingDB Entry DOI: 10.7270/Q2SF2ZMN
					More data for this Ligand-Target Pair