BDBM50470221 CHEMBL78445

SMILES: CCCCc1nc(SC)c(C(=O)NC)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)NCCC

InChI Key: InChIKey=IBDSUWYKDBAYOC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50470221   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Angiotensin II receptor (AT-1) type-1 (RAT)	BDBM50470221 (CHEMBL78445) Show SMILES CCCCc1nc(SC)c(C(=O)NC)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)NCCC Show InChI InChI=1S/C27H35N5O4S2/c1-5-7-12-23-30-26(37-4)24(25(33)28-3)32(23)18-19-13-15-20(16-14-19)21-10-8-9-11-22(21)38(35,36)31-27(34)29-17-6-2/h8-11,13-16H,5-7,12,17-18H2,1-4H3,(H,28,33)(H2,29,31,34)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
Hoechst Roussel PGU Cardiovascular Agents Curated by ChEMBL					Assay Description Specific binding inhibition of [125I]AII to Angiotensin II receptor, type 1 in rat liver membrane				J Med Chem 38: 2357-77 (1995) Article DOI: 10.1021/jm00013a013 BindingDB Entry DOI: 10.7270/Q2KK9FH8
					More data for this Ligand-Target Pair