BDBM50470518 CHEMBL4294523

SMILES: CNc1ccc(Br)cc(C(=O)\C=C\c2c(Cl)cccc2Cl)c1=O

InChI Key: InChIKey=UAPOBKMRCWWKEA-SOFGYWHQSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50470518   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Signal transducer and activator of transcription 3 (Homo sapiens (Human))	BDBM50470518 (CHEMBL4294523) Show SMILES CNc1ccc(Br)cc(C(=O)\C=C\c2c(Cl)cccc2Cl)c1=O Show InChI InChI=1S/C17H12BrCl2NO2/c1-21-15-7-5-10(18)9-12(17(15)23)16(22)8-6-11-13(19)3-2-4-14(11)20/h2-9H,1H3,(H,21,23)/b8-6+	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	740	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Medical Sciences and Peking Union Medical College Curated by ChEMBL					Assay Description Inhibition of Cy5-labeled double-strand DNA probe binding to STAT3 (unknown origin) expressed in H1299 cell lysates assessed as decrease in DNA bindi...				Eur J Med Chem 157: 887-897 (2018) Article DOI: 10.1016/j.ejmech.2018.08.037 BindingDB Entry DOI: 10.7270/Q27M0BNN
					More data for this Ligand-Target Pair