BDBM50470676 CHEMBL359255

SMILES: COc1ccc(cc1CN[C@H]1CCCN[C@H]1c1ccccc1)-n1cncn1

InChI Key: InChIKey=UEVAJSKRFJXQKF-FPOVZHCZSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50470676   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neurokinin 1 receptor (Homo sapiens (Human))	BDBM50470676 (CHEMBL359255) Show SMILES COc1ccc(cc1CN[C@H]1CCCN[C@H]1c1ccccc1)-n1cncn1 Show InChI InChI=1S/C21H25N5O/c1-27-20-10-9-18(26-15-22-14-25-26)12-17(20)13-24-19-8-5-11-23-21(19)16-6-3-2-4-7-16/h2-4,6-7,9-10,12,14-15,19,21,23-24H,5,8,11,13H2,1H3/t19-,21-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.158	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GSK UK Curated by ChEMBL					Assay Description Binding affinity to Tachykinin receptor 1 stably expressed in chinese hamster ovary (CHO) cells				J Med Chem 38: 4985-92 (1995) Article DOI: 10.1021/jm00026a005 BindingDB Entry DOI: 10.7270/Q2S46VQ5
					More data for this Ligand-Target Pair