null
SMILES: COc1ccc2Cc3ccn(CC(C)N)c3-c2c1
InChI Key: InChIKey=OTCPUISFVUWAGR-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50471314 (CHEMBL414163) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
F. Hoffmann-La Roche Inc Curated by ChEMBL | Assay Description Binding affinity against human 5-hydroxytryptamine 2C receptor using displacement of [3H]DOB | J Med Chem 40: 2762-9 (1997) Article DOI: 10.1021/jm970030l BindingDB Entry DOI: 10.7270/Q270845Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (Homo sapiens (Human)) | BDBM50471314 (CHEMBL414163) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 126 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
F. Hoffmann-La Roche Inc Curated by ChEMBL | Assay Description Binding affinity against human 5-hydroxytryptamine 2A receptor using displacement of [3H]5-HT | J Med Chem 40: 2762-9 (1997) Article DOI: 10.1021/jm970030l BindingDB Entry DOI: 10.7270/Q270845Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Rattus norvegicus (Rat)) | BDBM50471314 (CHEMBL414163) | KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 398 | n/a | n/a | n/a | n/a |
F. Hoffmann-La Roche Inc Curated by ChEMBL | Assay Description Efficacy (pEC50) was evaluated for 5-HT2C receptor-mediated stimulation of IP3 formation in vitro in choroid plexus of the rat | J Med Chem 40: 2762-9 (1997) Article DOI: 10.1021/jm970030l BindingDB Entry DOI: 10.7270/Q270845Q | |||||||||||
More data for this Ligand-Target Pair |