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BDBM50473042 CHEMBL141269

SMILES: OC(C(=O)OC1CCN(Cc2ccc(F)cc2)CC1)(c1ccccc1)c1ccccc1

InChI Key: InChIKey=VFMONUOYFULIIW-UHFFFAOYSA-N

Data: 1 KI

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50473042   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Muscarinic acetylcholine receptor


(RAT)		BDBM50473042
PNG
(CHEMBL141269)
Show SMILES OC(C(=O)OC1CCN(Cc2ccc(F)cc2)CC1)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C26H26FNO3/c27-23-13-11-20(12-14-23)19-28-17-15-24(16-18-28)31-25(29)26(30,21-7-3-1-4-8-21)22-9-5-2-6-10-22/h1-14,24,30H,15-19H2
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
 0.160n/an/an/an/an/an/an/an/a



University of Michigan Medical School

Curated by ChEMBL


Assay Description
In vitro for binding affinity for muscarinic acetylcholine receptors in homogenized rat brain in the presence of [3H]scopolamine.

J Med Chem 43: 4552-62 (2000)


Article DOI: 10.1021/jm000305o
BindingDB Entry DOI: 10.7270/Q29889RS
More data for this
Ligand-Target Pair