BDBM50473209 CHEMBL20958

SMILES: CCCCn1c2ncn(c2c(=O)n(CCCC)c1=O)S(=O)(=O)c1ccccc1C(=O)OC

InChI Key: InChIKey=GZMPVUPEEMXMQY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50473209   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphodiesterase 4 (Homo sapiens (Human))	BDBM50473209 (CHEMBL20958) Show SMILES CCCCn1c2ncn(c2c(=O)n(CCCC)c1=O)S(=O)(=O)c1ccccc1C(=O)OC Show InChI InChI=1S/C21H26N4O6S/c1-4-6-12-23-18-17(19(26)24(21(23)28)13-7-5-2)25(14-22-18)32(29,30)16-11-9-8-10-15(16)20(27)31-3/h8-11,14H,4-7,12-13H2,1-3H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth-Ayerst Research Curated by ChEMBL					Assay Description Concentration at which 50% of the activity of the Phosphodiesterase 4 from Human U937 cells is inhibited				J Med Chem 43: 1223-33 (2000) Article DOI: 10.1021/jm990558l BindingDB Entry DOI: 10.7270/Q2NK3HRK
					More data for this Ligand-Target Pair