null

SMILES: COc1ccccc1OCCN1CCN(CC1)c1ccc(=O)n(CCCCN2CCN(CC2)c2ccccc2Cl)n1

InChI Key: InChIKey=LSRWHOCLZIQMCF-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50473245   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50473245 (CHEMBL68052) Show SMILES COc1ccccc1OCCN1CCN(CC1)c1ccc(=O)n(CCCCN2CCN(CC2)c2ccccc2Cl)n1 Show InChI InChI=1S/C31H41ClN6O3/c1-40-28-10-4-5-11-29(28)41-25-24-35-18-22-37(23-19-35)30-12-13-31(39)38(33-30)15-7-6-14-34-16-20-36(21-17-34)27-9-3-2-8-26(27)32/h2-5,8-13H,6-7,14-25H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Perugia Curated by ChEMBL					Assay Description Binding affinity towards alpha-1 adrenergic receptor in rat cortex membrane using [3H]-prazosin radioligand				J Med Chem 44: 2118-32 (2001) Article DOI: 10.1021/jm010821u BindingDB Entry DOI: 10.7270/Q2W3802N
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor (RAT-NEONATAL RAT-Rattus norvegicus (rat))	BDBM50473245 (CHEMBL68052) Show SMILES COc1ccccc1OCCN1CCN(CC1)c1ccc(=O)n(CCCCN2CCN(CC2)c2ccccc2Cl)n1 Show InChI InChI=1S/C31H41ClN6O3/c1-40-28-10-4-5-11-29(28)41-25-24-35-18-22-37(23-19-35)30-12-13-31(39)38(33-30)15-7-6-14-34-16-20-36(21-17-34)27-9-3-2-8-26(27)32/h2-5,8-13H,6-7,14-25H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	69	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Perugia Curated by ChEMBL					Assay Description Binding affinity towards alpha-2 adrenergic receptor in rat cortex membrane using [3H]rauwolscine radioligand				J Med Chem 44: 2118-32 (2001) Article DOI: 10.1021/jm010821u BindingDB Entry DOI: 10.7270/Q2W3802N
					More data for this Ligand-Target Pair