null

SMILES: COc1ccccc1OCCN1CCN(CC1)c1cnn(CCCCCN2CCN(CC2)c2ccccc2Cl)c(=O)c1Cl

InChI Key: InChIKey=CBYOVXGNAZQSRG-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50473255   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50473255 (CHEMBL303894) Show SMILES COc1ccccc1OCCN1CCN(CC1)c1cnn(CCCCCN2CCN(CC2)c2ccccc2Cl)c(=O)c1Cl Show InChI InChI=1S/C32H42Cl2N6O3/c1-42-29-11-5-6-12-30(29)43-24-23-37-17-21-39(22-18-37)28-25-35-40(32(41)31(28)34)14-8-2-7-13-36-15-19-38(20-16-36)27-10-4-3-9-26(27)33/h3-6,9-12,25H,2,7-8,13-24H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	4.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Perugia Curated by ChEMBL					Assay Description Binding affinity towards alpha-1 adrenergic receptor in rat cortex membrane using [3H]-prazosin radioligand				J Med Chem 44: 2118-32 (2001) Article DOI: 10.1021/jm010821u BindingDB Entry DOI: 10.7270/Q2W3802N
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor (RAT-NEONATAL RAT-Rattus norvegicus (rat))	BDBM50473255 (CHEMBL303894) Show SMILES COc1ccccc1OCCN1CCN(CC1)c1cnn(CCCCCN2CCN(CC2)c2ccccc2Cl)c(=O)c1Cl Show InChI InChI=1S/C32H42Cl2N6O3/c1-42-29-11-5-6-12-30(29)43-24-23-37-17-21-39(22-18-37)28-25-35-40(32(41)31(28)34)14-8-2-7-13-36-15-19-38(20-16-36)27-10-4-3-9-26(27)33/h3-6,9-12,25H,2,7-8,13-24H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	29	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Perugia Curated by ChEMBL					Assay Description Binding affinity towards alpha-2 adrenergic receptor in rat cortex membrane using [3H]rauwolscine radioligand				J Med Chem 44: 2118-32 (2001) Article DOI: 10.1021/jm010821u BindingDB Entry DOI: 10.7270/Q2W3802N
					More data for this Ligand-Target Pair