BDBM50473267 CHEMBL67379

SMILES: Clc1ccccc1N1CCN(CCn2ncc(N3CCN(CC3)C(=O)c3ccco3)c(Cl)c2=O)CC1

InChI Key: InChIKey=LCRBRIXRBALAPX-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50473267   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50473267 (CHEMBL67379) Show SMILES Clc1ccccc1N1CCN(CCn2ncc(N3CCN(CC3)C(=O)c3ccco3)c(Cl)c2=O)CC1 Show InChI InChI=1S/C25H28Cl2N6O3/c26-19-4-1-2-5-20(19)30-10-7-29(8-11-30)9-16-33-25(35)23(27)21(18-28-33)31-12-14-32(15-13-31)24(34)22-6-3-17-36-22/h1-6,17-18H,7-16H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Perugia Curated by ChEMBL					Assay Description Binding affinity towards alpha-1 adrenergic receptor in rat cortex membrane using [3H]-prazosin radioligand				J Med Chem 44: 2118-32 (2001) Article DOI: 10.1021/jm010821u BindingDB Entry DOI: 10.7270/Q2W3802N
					More data for this Ligand-Target Pair
Adrenergic receptor alpha-2 (RAT-NEONATAL RAT-Rattus norvegicus (rat))	BDBM50473267 (CHEMBL67379) Show SMILES Clc1ccccc1N1CCN(CCn2ncc(N3CCN(CC3)C(=O)c3ccco3)c(Cl)c2=O)CC1 Show InChI InChI=1S/C25H28Cl2N6O3/c26-19-4-1-2-5-20(19)30-10-7-29(8-11-30)9-16-33-25(35)23(27)21(18-28-33)31-12-14-32(15-13-31)24(34)22-6-3-17-36-22/h1-6,17-18H,7-16H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Perugia Curated by ChEMBL					Assay Description Binding affinity towards alpha-2 adrenergic receptor in rat cortex membrane using [3H]rauwolscine radioligand				J Med Chem 44: 2118-32 (2001) Article DOI: 10.1021/jm010821u BindingDB Entry DOI: 10.7270/Q2W3802N
					More data for this Ligand-Target Pair