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SMILES: COc1ccc(Cl)cc1N1CCN(CCCn2nc(-c3ccccc3)c3c(C)onc3c2=O)CC1

InChI Key: InChIKey=BTWXPULWZUPULT-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50473281   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor


(Rattus norvegicus (rat)-Rattus norvegicus (Rat))		BDBM50473281
PNG
(CHEMBL441444)
Show SMILES COc1ccc(Cl)cc1N1CCN(CCCn2nc(-c3ccccc3)c3c(C)onc3c2=O)CC1
Show InChI InChI=1S/C26H28ClN5O3/c1-18-23-24(19-7-4-3-5-8-19)28-32(26(33)25(23)29-35-18)12-6-11-30-13-15-31(16-14-30)21-17-20(27)9-10-22(21)34-2/h3-5,7-10,17H,6,11-16H2,1-2H3
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PC cid
PC sid
UniChem
Article
PubMed
 7.90n/an/an/an/an/an/an/an/a



Universit£ di Perugia

Curated by ChEMBL


Assay Description
Binding affinity towards alpha-1 adrenergic receptor in rat cortex membrane using [3H]-prazosin radioligand

J Med Chem 44: 2118-32 (2001)


Article DOI: 10.1021/jm010821u
BindingDB Entry DOI: 10.7270/Q2W3802N
More data for this
Ligand-Target Pair