null

SMILES: COc1ccccc1OCCN1CCN(CC1)c1ccc(=O)n(CCCCCCN2CCN(CC2)c2ccccc2Cl)n1

InChI Key: InChIKey=UHUOEEIBKSZATP-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50473297   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50473297 (CHEMBL306440) Show SMILES COc1ccccc1OCCN1CCN(CC1)c1ccc(=O)n(CCCCCCN2CCN(CC2)c2ccccc2Cl)n1 Show InChI InChI=1S/C33H45ClN6O3/c1-42-30-12-6-7-13-31(30)43-27-26-37-20-24-39(25-21-37)32-14-15-33(41)40(35-32)17-9-3-2-8-16-36-18-22-38(23-19-36)29-11-5-4-10-28(29)34/h4-7,10-15H,2-3,8-9,16-27H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	8.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Perugia Curated by ChEMBL					Assay Description Binding affinity towards alpha-1 adrenergic receptor in rat cortex membrane using [3H]-prazosin radioligand				J Med Chem 44: 2118-32 (2001) Article DOI: 10.1021/jm010821u BindingDB Entry DOI: 10.7270/Q2W3802N
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor (RAT-NEONATAL RAT-Rattus norvegicus (rat))	BDBM50473297 (CHEMBL306440) Show SMILES COc1ccccc1OCCN1CCN(CC1)c1ccc(=O)n(CCCCCCN2CCN(CC2)c2ccccc2Cl)n1 Show InChI InChI=1S/C33H45ClN6O3/c1-42-30-12-6-7-13-31(30)43-27-26-37-20-24-39(25-21-37)32-14-15-33(41)40(35-32)17-9-3-2-8-16-36-18-22-38(23-19-36)29-11-5-4-10-28(29)34/h4-7,10-15H,2-3,8-9,16-27H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	139	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Perugia Curated by ChEMBL					Assay Description Binding affinity towards alpha-2 adrenergic receptor in rat cortex membrane using [3H]rauwolscine radioligand				J Med Chem 44: 2118-32 (2001) Article DOI: 10.1021/jm010821u BindingDB Entry DOI: 10.7270/Q2W3802N
					More data for this Ligand-Target Pair