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SMILES: COc1ccccc1CN1N=C(C2CCCCC2C1=O)c1ccc(OC)c(OC)c1

InChI Key: InChIKey=HVZVPGFXFPHGPA-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50473706   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D


(Homo sapiens (Human))		BDBM50473706
PNG
(CHEMBL419303)
Show SMILES COc1ccccc1CN1N=C(C2CCCCC2C1=O)c1ccc(OC)c(OC)c1 |c:11|
Show InChI InChI=1S/C24H28N2O4/c1-28-20-11-7-4-8-17(20)15-26-24(27)19-10-6-5-9-18(19)23(25-26)16-12-13-21(29-2)22(14-16)30-3/h4,7-8,11-14,18-19H,5-6,9-10,15H2,1-3H3
PDB

UniProtKB/SwissProt

antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 20n/an/an/an/an/an/a



Vrije Universiteit

Curated by ChEMBL


Assay Description
Inhibitory concentration against phosphodiesterase 4 (PDE4) in cytosol of human neutrophils

J Med Chem 45: 2520-5 (2002)


Article DOI: 10.1021/jm0110340
BindingDB Entry DOI: 10.7270/Q2862K56
More data for this
Ligand-Target Pair