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SMILES: COc1ccc(cc1OC)C1=NN(CCCCN(C)C)C(=O)C2CCCCC12

InChI Key: InChIKey=ZFPQQBRXDLRJDH-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50473710   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
cAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D


(Homo sapiens (Human))		BDBM50473710
PNG
(CHEMBL86181)
Show SMILES COc1ccc(cc1OC)C1=NN(CCCCN(C)C)C(=O)C2CCCCC12 |t:11|
Show InChI InChI=1S/C22H33N3O3/c1-24(2)13-7-8-14-25-22(26)18-10-6-5-9-17(18)21(23-25)16-11-12-19(27-3)20(15-16)28-4/h11-12,15,17-18H,5-10,13-14H2,1-4H3
PDB

UniProtKB/SwissProt

antibodypedia
antibodypedia
antibodypedia
antibodypedia
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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 100n/an/an/an/an/an/a



Vrije Universiteit

Curated by ChEMBL


Assay Description
Inhibitory concentration against phosphodiesterase 4 (PDE4) in cytosol of human neutrophils

J Med Chem 45: 2520-5 (2002)


Article DOI: 10.1021/jm0110340
BindingDB Entry DOI: 10.7270/Q2862K56
More data for this
Ligand-Target Pair