BDBM50473884 CHEMBL421633
SMILES: [H][C@]12Cc3ccc(O)cc3C(C)(CCN1CC(C)OC)C2(C)C
InChI Key: InChIKey=ZZDBWKNXQCIZFX-IUNXBHMESA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sodium channel protein type 1/2/3 subunit alpha (Rattus norvegicus) | BDBM50473884 (CHEMBL421633) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 6.01E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG Curated by ChEMBL | Assay Description Displacement of [3H]BTX from sodium channel of rat cerebral cortex synaptosomes | J Med Chem 45: 3755-64 (2002) Article DOI: 10.1021/jm020875j BindingDB Entry DOI: 10.7270/Q2ZS308Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 1/2/3 subunit alpha (Rattus norvegicus) | BDBM50473884 (CHEMBL421633) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG Curated by ChEMBL | Assay Description Inhibitory effect against veratridine-induced glutamate release from rat brain slices | J Med Chem 45: 3755-64 (2002) Article DOI: 10.1021/jm020875j BindingDB Entry DOI: 10.7270/Q2ZS308Z | |||||||||||
More data for this Ligand-Target Pair |