BDBM50473885 CHEMBL2112618
SMILES: [H][C@@]12Cc3cc(O)ccc3C(C)(CCN1C[C@H](C)OCc1ccccc1)C2(C)C
InChI Key: InChIKey=UDESXJATSXUHTE-CFSTZMPOSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sodium channel protein type 1/2/3 subunit alpha (Rattus norvegicus) | BDBM50473885 (CHEMBL2112618) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 1.87E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG Curated by ChEMBL | Assay Description Displacement of [3H]BTX from sodium channel of rat cerebral cortex synaptosomes | J Med Chem 45: 3755-64 (2002) Article DOI: 10.1021/jm020875j BindingDB Entry DOI: 10.7270/Q2ZS308Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 1/2/3 subunit alpha (Rattus norvegicus) | BDBM50473885 (CHEMBL2112618) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4.52E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharma KG Curated by ChEMBL | Assay Description Inhibitory effect against veratridine-induced glutamate release from rat brain slices | J Med Chem 45: 3755-64 (2002) Article DOI: 10.1021/jm020875j BindingDB Entry DOI: 10.7270/Q2ZS308Z | |||||||||||
More data for this Ligand-Target Pair |