null

SMILES: Fc1ccc(cc1)C(OCCN1CCN(C\C=C\Cc2ccccc2)CC1)c1ccc(F)cc1

InChI Key: InChIKey=KLDSCOWYMZLTGO-SNAWJCMRSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50474027   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50474027 (CHEMBL40415) Show SMILES Fc1ccc(cc1)C(OCCN1CCN(C\C=C\Cc2ccccc2)CC1)c1ccc(F)cc1 Show InChI InChI=1S/C29H32F2N2O/c30-27-13-9-25(10-14-27)29(26-11-15-28(31)16-12-26)34-23-22-33-20-18-32(19-21-33)17-5-4-8-24-6-2-1-3-7-24/h1-7,9-16,29H,8,17-23H2/b5-4+	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	72	n/a	n/a	n/a	n/a	n/a
Universit£ di Perugia Curated by ChEMBL					Assay Description Inhibition of [125I]RTI-55 binding to human SERT in clonal cells				J Med Chem 45: 1577-84 (2002) Article DOI: 10.1021/jm011007+ BindingDB Entry DOI: 10.7270/Q29026JT
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM50474027 (CHEMBL40415) Show SMILES Fc1ccc(cc1)C(OCCN1CCN(C\C=C\Cc2ccccc2)CC1)c1ccc(F)cc1 Show InChI InChI=1S/C29H32F2N2O/c30-27-13-9-25(10-14-27)29(26-11-15-28(31)16-12-26)34-23-22-33-20-18-32(19-21-33)17-5-4-8-24-6-2-1-3-7-24/h1-7,9-16,29H,8,17-23H2/b5-4+	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	5.10	n/a	n/a	n/a	n/a	n/a
Universit£ di Perugia Curated by ChEMBL					Assay Description Inhibition of radioligand [125I]RTI-55 binding to human Dopamine transporter in clonal cells				J Med Chem 45: 1577-84 (2002) Article DOI: 10.1021/jm011007+ BindingDB Entry DOI: 10.7270/Q29026JT
					More data for this Ligand-Target Pair