BDBM50474235 CHEMBL3349606
SMILES: [H][C@@]12C[C@H](CN1C(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccc(OCc3ccccc3)cc1)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](Cc1c[nH]c3ccccc13)NC(=O)[C@H](Cc1ccccc1)NC2=O)OC(=O)NCCN(C)C
InChI Key: InChIKey=GHKLZOPUCYNDCD-SJSJVHPDSA-N
Data: 5 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Somatostatin receptor type 5 (Homo sapiens (Human)) | BDBM50474235 (CHEMBL3349606) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Pharma Curated by ChEMBL | Assay Description Binding affinity towards human Somatostatin receptor type 5 (sst5) using Tyr11-[125I]-SRIF as radioligand was determined in COS cell | J Med Chem 46: 2334-44 (2003) Article DOI: 10.1021/jm021093t BindingDB Entry DOI: 10.7270/Q2CR5X31 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Somatostatin receptor type 3 (Homo sapiens (Human)) | BDBM50474235 (CHEMBL3349606) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.316 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Pharma Curated by ChEMBL | Assay Description Binding affinity towards human Somatostatin receptor type 3 (sst3) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells | J Med Chem 46: 2334-44 (2003) Article DOI: 10.1021/jm021093t BindingDB Entry DOI: 10.7270/Q2CR5X31 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Somatostatin receptor type 2 (Homo sapiens (Human)) | BDBM50474235 (CHEMBL3349606) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 0.501 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Pharma Curated by ChEMBL | Assay Description Binding affinity towards human Somatostatin receptor type 2 (sst2) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells | J Med Chem 46: 2334-44 (2003) Article DOI: 10.1021/jm021093t BindingDB Entry DOI: 10.7270/Q2CR5X31 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Somatostatin receptor type 1 (Homo sapiens (Human)) | BDBM50474235 (CHEMBL3349606) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Pharma Curated by ChEMBL | Assay Description Binding affinity towards human Somatostatin receptor type 1 (sst1) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells | J Med Chem 46: 2334-44 (2003) Article DOI: 10.1021/jm021093t BindingDB Entry DOI: 10.7270/Q2CR5X31 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Somatostatin receptor type 4 (Homo sapiens (Human)) | BDBM50474235 (CHEMBL3349606) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | <100 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Pharma Curated by ChEMBL | Assay Description Binding affinity towards human Somatostatin receptor type 4 (sst4) using Tyr11-[125I]-SRIF as radioligand was determined in CHO cells | J Med Chem 46: 2334-44 (2003) Article DOI: 10.1021/jm021093t BindingDB Entry DOI: 10.7270/Q2CR5X31 | |||||||||||
More data for this Ligand-Target Pair |