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SMILES: ONC(=O)\C=C\c1ccc(CNCCOc2ccccc2)cc1

InChI Key: InChIKey=LTSQRCBVRANAJI-ZHACJKMWSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50474349   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histone deacetylase 1/2/3/4/5/6/7/8/9/11/Polyamine deacetylase HDAC10


(Homo sapiens (Human))		BDBM50474349
PNG
(CHEMBL140899)
Show SMILES ONC(=O)\C=C\c1ccc(CNCCOc2ccccc2)cc1
Show InChI InChI=1S/C18H20N2O3/c21-18(20-22)11-10-15-6-8-16(9-7-15)14-19-12-13-23-17-4-2-1-3-5-17/h1-11,19,22H,12-14H2,(H,20,21)/b11-10+
PDB

UniProtKB/SwissProt

antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 69n/an/an/an/an/an/a



Novartis Institute for Biomedical Research

Curated by ChEMBL


Assay Description
Inhibitory activity against histone deacetylase (HDAC) enzyme obtained from H1299 human lung carcinoma cell lysates

J Med Chem 46: 4609-24 (2003)


Article DOI: 10.1021/jm030235w
BindingDB Entry DOI: 10.7270/Q2736TP0
More data for this
Ligand-Target Pair