BDBM50475352 CHEMBL179479

SMILES: C(Cc1ccccc1)N1CCC(CC1)=Cc1c[nH]cn1

InChI Key: InChIKey=DWKRHNOHHBZGFS-UHFFFAOYSA-N

Data: 1 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50475352   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Homo sapiens (Human))	BDBM50475352 (CHEMBL179479) Show SMILES C(Cc1ccccc1)N1CCC(CC1)=Cc1c[nH]cn1 |(1.75,.79,;3.05,-.03,;4.42,.67,;5.67,-.16,;7.05,.53,;7.14,2.08,;5.86,2.91,;4.48,2.21,;.4,.04,;.36,-1.49,;-1.02,-2.22,;-2.32,-1.41,;-2.28,.14,;-.9,.86,;-3.68,-2.12,;-4.97,-1.34,;-6.46,-1.78,;-7.32,-.49,;-6.39,.72,;-4.96,.19,)| Show InChI InChI=1S/C17H21N3/c1-2-4-15(5-3-1)6-9-20-10-7-16(8-11-20)12-17-13-18-14-19-17/h1-5,12-14H,6-11H2,(H,18,19)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	63	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vrije Universiteit Amsterdam Curated by ChEMBL					Assay Description Displacement of [3H]N-R-methylhistamine binding to SK-N-MC cell membranes expressing human H3 receptor				J Med Chem 48: 2100-7 (2005) Article DOI: 10.1021/jm049475h BindingDB Entry DOI: 10.7270/Q28K7CVC
					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50475352 (CHEMBL179479) Show SMILES C(Cc1ccccc1)N1CCC(CC1)=Cc1c[nH]cn1 |(1.75,.79,;3.05,-.03,;4.42,.67,;5.67,-.16,;7.05,.53,;7.14,2.08,;5.86,2.91,;4.48,2.21,;.4,.04,;.36,-1.49,;-1.02,-2.22,;-2.32,-1.41,;-2.28,.14,;-.9,.86,;-3.68,-2.12,;-4.97,-1.34,;-6.46,-1.78,;-7.32,-.49,;-6.39,.72,;-4.96,.19,)| Show InChI InChI=1S/C17H21N3/c1-2-4-15(5-3-1)6-9-20-10-7-16(8-11-20)12-17-13-18-14-19-17/h1-5,12-14H,6-11H2,(H,18,19)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	16	n/a	n/a	n/a	n/a
Vrije Universiteit Amsterdam Curated by ChEMBL					Assay Description Inhibition of cAMP-stimulated beta-galactosidase transcription in SK-N-MC cells expressing human H3 receptor				J Med Chem 48: 2100-7 (2005) Article DOI: 10.1021/jm049475h BindingDB Entry DOI: 10.7270/Q28K7CVC
					More data for this Ligand-Target Pair