BDBM50475561 CHEMBL380339

SMILES: CC(Sc1ccc(cc1)N(C)C)\C=C(/C)\C=C\C(=O)NO

InChI Key: InChIKey=RTUXHWGTLOLXLW-WKWSCTOISA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50475561   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 1/2/3/4/5/6/7/8/9/11/Polyamine deacetylase HDAC10 (Homo sapiens (Human))	BDBM50475561 (CHEMBL380339) Show SMILES CC(Sc1ccc(cc1)N(C)C)\C=C(/C)\C=C\C(=O)NO Show InChI InChI=1S/C16H22N2O2S/c1-12(5-10-16(19)17-20)11-13(2)21-15-8-6-14(7-9-15)18(3)4/h5-11,13,20H,1-4H3,(H,17,19)/b10-5+,12-11+	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description Inhibition of HDAC in human leukemic CEM cells				J Med Chem 49: 800-5 (2006) Article DOI: 10.1021/jm051010j BindingDB Entry DOI: 10.7270/Q2JW8HN9
					More data for this Ligand-Target Pair
Histone deacetylase (Rattus norvegicus)	BDBM50475561 (CHEMBL380339) Show SMILES CC(Sc1ccc(cc1)N(C)C)\C=C(/C)\C=C\C(=O)NO Show InChI InChI=1S/C16H22N2O2S/c1-12(5-10-16(19)17-20)11-13(2)21-15-8-6-14(7-9-15)18(3)4/h5-11,13,20H,1-4H3,(H,17,19)/b10-5+,12-11+	UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	340	n/a	n/a	n/a	n/a	n/a	n/a
University College London Curated by ChEMBL					Assay Description Inhibition of HDAC in rat liver homogenate				J Med Chem 49: 800-5 (2006) Article DOI: 10.1021/jm051010j BindingDB Entry DOI: 10.7270/Q2JW8HN9
					More data for this Ligand-Target Pair