BDBM50475895 CHEMBL385254

SMILES: COc1cc(NC(=O)c2ccc(cc2)-c2ccccc2)ccc1OCCN(C(C)C)C(C)C

InChI Key: InChIKey=RZJWWQSGWHXWAK-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50475895   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50475895 (CHEMBL385254) Show SMILES COc1cc(NC(=O)c2ccc(cc2)-c2ccccc2)ccc1OCCN(C(C)C)C(C)C Show InChI InChI=1S/C28H34N2O3/c1-20(2)30(21(3)4)17-18-33-26-16-15-25(19-27(26)32-5)29-28(31)24-13-11-23(12-14-24)22-9-7-6-8-10-22/h6-16,19-21H,17-18H2,1-5H3,(H,29,31)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	32	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Displacement of radiolabeled iodo-MCH from human MCHR1 expressed in HEK293 cells				Bioorg Med Chem Lett 16: 4865-71 (2006) Article DOI: 10.1016/j.bmcl.2006.06.056 BindingDB Entry DOI: 10.7270/Q2F192GH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50475895 (CHEMBL385254) Show SMILES COc1cc(NC(=O)c2ccc(cc2)-c2ccccc2)ccc1OCCN(C(C)C)C(C)C Show InChI InChI=1S/C28H34N2O3/c1-20(2)30(21(3)4)17-18-33-26-16-15-25(19-27(26)32-5)29-28(31)24-13-11-23(12-14-24)22-9-7-6-8-10-22/h6-16,19-21H,17-18H2,1-5H3,(H,29,31)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	158	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Binding affinity to 5HT2C receptor				Bioorg Med Chem Lett 16: 4865-71 (2006) Article DOI: 10.1016/j.bmcl.2006.06.056 BindingDB Entry DOI: 10.7270/Q2F192GH
					More data for this Ligand-Target Pair