BDBM50475901 CHEMBL214577

SMILES: COc1cc(NC(=O)c2ccc(cc2)-c2cccc(c2)C(F)(F)F)ccc1OCCN(C(C)C)C(C)C

InChI Key: InChIKey=SSZUGNCZYQRLDG-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50475901   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM50475901 (CHEMBL214577) Show SMILES COc1cc(NC(=O)c2ccc(cc2)-c2cccc(c2)C(F)(F)F)ccc1OCCN(C(C)C)C(C)C Show InChI InChI=1S/C29H33F3N2O3/c1-19(2)34(20(3)4)15-16-37-26-14-13-25(18-27(26)36-5)33-28(35)22-11-9-21(10-12-22)23-7-6-8-24(17-23)29(30,31)32/h6-14,17-20H,15-16H2,1-5H3,(H,33,35)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	251	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Displacement of radiolabeled iodo-MCH from human MCHR1 expressed in HEK293 cells				Bioorg Med Chem Lett 16: 4865-71 (2006) Article DOI: 10.1016/j.bmcl.2006.06.056 BindingDB Entry DOI: 10.7270/Q2F192GH
					More data for this Ligand-Target Pair