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SMILES: CN(C)c1ccc(\C=C\c2cnc(OCCO)c(I)c2)cc1

InChI Key: InChIKey=WPWFHGOKCHAUPZ-ONEGZZNKSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50476280   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Amyloid-beta precursor protein


(Homo sapiens (Human))		BDBM50476280
PNG
(CHEMBL224148)
Show SMILES CN(C)c1ccc(\C=C\c2cnc(OCCO)c(I)c2)cc1
Show InChI InChI=1S/C17H19IN2O2/c1-20(2)15-7-5-13(6-8-15)3-4-14-11-16(18)17(19-12-14)22-10-9-21/h3-8,11-12,21H,9-10H2,1-2H3/b4-3+
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 7.5n/an/an/an/an/an/an/an/a



University of Pennsylvania

Curated by ChEMBL


Assay Description
Displacement of [15I]IMPY from Abeta peptide plaques in Alzheimer's disease patient brain

J Med Chem 50: 2157-65 (2007)


Article DOI: 10.1021/jm070025+
BindingDB Entry DOI: 10.7270/Q21N83WD
More data for this
Ligand-Target Pair