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SMILES: Nc1ccc(cc1)C#Cc1ccc(N)cc1

InChI Key: InChIKey=WAUKJWLKPXRNKT-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50476290   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Amyloid-beta precursor protein


(Homo sapiens (Human))		BDBM50476290
PNG
(CHEMBL227625)
Show SMILES Nc1ccc(cc1)C#Cc1ccc(N)cc1
Show InChI InChI=1S/C14H12N2/c15-13-7-3-11(4-8-13)1-2-12-5-9-14(16)10-6-12/h3-10H,15-16H2
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MMDB

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Article
PubMed
 76n/an/an/an/an/an/an/an/a



University of Pennsylvania

Curated by ChEMBL


Assay Description
Displacement of [125I]IMPY from human beta amyloid plaque in brain homogenates

J Med Chem 50: 2415-23 (2007)


Article DOI: 10.1021/jm070090j
BindingDB Entry DOI: 10.7270/Q2S46VS2
More data for this
Ligand-Target Pair