BDBM50476391 CHEMBL447845

SMILES: [#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6]\[#6]=[#6](\[#6])-[#6])=[#6]\[#6]-[#8]P([#8])([#8])=O

InChI Key: InChIKey=WVVHHGHQAUECIR-PYPMKZSKSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50476391   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein Farnesyltransferase (PFT) (Homo sapiens (Human))	BDBM50476391 (CHEMBL447845) Show SMILES [#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6])=[#6]\[#6]-[#6]\[#6](-[#6]\[#6]=[#6](\[#6])-[#6])=[#6]\[#6]-[#8]P([#8])([#8])=O Show InChI InChI=1S/C19H33O4P/c1-16(2)8-6-9-18(5)10-7-11-19(13-12-17(3)4)14-15-23-24(20,21)22/h8,10,12,14H,6-7,9,11,13,15H2,1-5H3,(H2,20,21,22)/b18-10+,19-14-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Purdue University Curated by ChEMBL					Assay Description Inhibition of farnesyltransferase assessed as farnesylation of Dansyl-GCVLS peptide				J Med Chem 50: 3274-82 (2007) Article DOI: 10.1021/jm0701829 BindingDB Entry DOI: 10.7270/Q2R49TJB
					More data for this Ligand-Target Pair