null

SMILES: C1CN=C(Nc2ccc(Nc3ccc(NC4=NCCN4)cc3)cc2)N1

InChI Key: InChIKey=AJWTXSLKVJNYAB-UHFFFAOYSA-N

PDB links: 2 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50476630   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-2A/Alpha-2B/Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50476630 (CHEMBL242102) Show SMILES C1CN=C(Nc2ccc(Nc3ccc(NC4=NCCN4)cc3)cc2)N1 |t:2,15| Show InChI InChI=1S/C18H21N7/c1-5-15(24-17-19-9-10-20-17)6-2-13(1)23-14-3-7-16(8-4-14)25-18-21-11-12-22-18/h1-8,23H,9-12H2,(H2,19,20,24)(H2,21,22,25)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	Article PubMed	58	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Dublin Curated by ChEMBL					Assay Description Displacement of [3H]RX821002 from adrenergic alpha2 receptor in human brain frontal cortex				J Med Chem 50: 4516-27 (2007) Article DOI: 10.1021/jm070229q BindingDB Entry DOI: 10.7270/Q2571FSN
					More data for this Ligand-Target Pair
Alpha-2A/Alpha-2B/Alpha-2C adrenergic receptor (Homo sapiens (Human))	BDBM50476630 (CHEMBL242102) Show SMILES C1CN=C(Nc2ccc(Nc3ccc(NC4=NCCN4)cc3)cc2)N1 |t:2,15| Show InChI InChI=1S/C18H21N7/c1-5-15(24-17-19-9-10-20-17)6-2-13(1)23-14-3-7-16(8-4-14)25-18-21-11-12-22-18/h1-8,23H,9-12H2,(H2,19,20,24)(H2,21,22,25)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	n/a	n/a	4.38E+3	n/a	n/a	n/a	n/a
University of Dublin Curated by ChEMBL					Assay Description Antagonist activity at human brain adrenergic alpha-2 receptor assessed as UK-14304-stimulated [35S]GTPgammaS binding at 10 uM				J Med Chem 50: 4516-27 (2007) Article DOI: 10.1021/jm070229q BindingDB Entry DOI: 10.7270/Q2571FSN
					More data for this Ligand-Target Pair