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SMILES: COc1ccc(NC2=NCCN2)cc1

InChI Key: InChIKey=ZCGHVGWHOPGTES-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50476635   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Alpha-2A/Alpha-2B/Alpha-2C adrenergic receptor


(Homo sapiens (Human))		BDBM50476635
PNG
(CHEMBL230644)
Show SMILES COc1ccc(NC2=NCCN2)cc1 |t:7|
Show InChI InChI=1S/C10H13N3O/c1-14-9-4-2-8(3-5-9)13-10-11-6-7-12-10/h2-5H,6-7H2,1H3,(H2,11,12,13)
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PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 3.04E+4n/an/an/an/a



University of Dublin

Curated by ChEMBL


Assay Description
Agonist activity at human brain adrenergic alpha2 receptor by [35S]GTPgammaS binding assay

J Med Chem 50: 4516-27 (2007)


Article DOI: 10.1021/jm070229q
BindingDB Entry DOI: 10.7270/Q2571FSN
More data for this
Ligand-Target Pair