BDBM50476675 CHEMBL233742

SMILES: COCCCN(C1CN(Cc2cncn2C)c2ccc(cc2C1)C#N)S(=O)(=O)c1cn(C)cn1

InChI Key: InChIKey=MTCBWDAIIYFYNS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50476675   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein Farnesyltransferase (PFT) (Homo sapiens (Human))	BDBM50476675 (CHEMBL233742) Show SMILES COCCCN(C1CN(Cc2cncn2C)c2ccc(cc2C1)C#N)S(=O)(=O)c1cn(C)cn1 Show InChI InChI=1S/C23H29N7O3S/c1-27-15-23(26-17-27)34(31,32)30(7-4-8-33-3)20-10-19-9-18(11-24)5-6-22(19)29(13-20)14-21-12-25-16-28(21)2/h5-6,9,12,15-17,20H,4,7-8,10,13-14H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.5	n/a	n/a	n/a	n/a	n/a	n/a
University of Washington Curated by ChEMBL					Assay Description Inhibition of protein farnesyltransferase				J Med Chem 50: 4585-605 (2007) Article DOI: 10.1021/jm0703340 BindingDB Entry DOI: 10.7270/Q2RX9FT9
					More data for this Ligand-Target Pair